UK Paediatric ITP Study Protocol

Below is a brief summary of the protocol. For the most up-to-date version, please click here to download

 

Summary

The UK Paediatric ITP Registry is a multi-centre study designed to collect prospective data on all new cases of childhood immune thrombocytopenic purpura (ITP).
The database will continue to collect data for many years about children whose ITP fails to resolve. Clinical data, bleeding severity, platelet counts and management will be recorded.

Aims

Primary Objectives:
The primary aim is to relate the long term consequences of a low platelet count to the frequency and severity of bleeding symptoms, and to the requirement for treatment.


Design

UK Chronic ITP Study design diagram

 


Data collection

Initial data will be recorded at presentation and at six months. Further data will be collected yearly on those with persistent ITP. Additional information will be requested in children with severe bleeds, intra-cranial bleeds or those requiring invasive dental work or surgery.